CHATPRIVACYDONATELOGINREGISTER
DMT-Nexus
FAQWIKIHEALTH & SAFETYARTATTITUDEACTIVE TOPICS
New research shows a link between Salvinorin A and the DMN Options
 
Jagube
#1 Posted : 12/22/2020 11:08:31 AM

DMT-Nexus member


Posts: 1048
Joined: 18-Feb-2017
Last visit: 30-Nov-2021
Quote:
The Default Mode Network (DMN) is by now a familiar name in popular psychedelic circles. It’s a collection of brain areas that talk loudly to each other when we’re not doing any focussed tasks – basically when we’re daydreaming, thinking about ourselves, or conceptualising the past or future.

We know two important things about the DMN: it’s overactive in depression, and psychedelics can help to reset it. Studies have shown that classic psychedelics LSD and psilocybin can dramatically reduce the chatter of the DMN during a psychedelic experience, and allow it to re-form itself into a more stable network afterwards – correlating with decreased depressive symptoms. [..]

Now, new research has shown that Salvinorin A is also connected to the DMN. Twelve experienced psychonauts were given doses of Salvinorin A while in an MRI machine, which showed that the unique psychedelic reduced the connectivity of the DMN in a very similar way to LSD and psilocybin.


https://thepsychedelicsc...lvinorin-a-and-the-dmn/

Original paper: https://www.nature.com/articles/s41598-020-73216-8
 

STS is a community for people interested in growing, preserving and researching botanical species, particularly those with remarkable therapeutic and/or psychoactive properties.
 
Cognitive Heart
#2 Posted : 12/22/2020 1:02:58 PM

DMT-Nexus member


Posts: 1892
Joined: 15-Mar-2014
Last visit: 22-Jul-2021
Incredible scientific report! Thank you for sharing. Love Thumbs up

I hope researchers can reduce their limitations in light of these findings. For anyone new to the default mode network or dynamical functions, start here: https://en.wikipedia.org/wiki/Dynamic_functional_connectivity
"What's going to happen?" "Something wonderful."
 
Loveall
#3 Posted : 1/27/2021 12:58:28 PM

💖

Chemical expertSenior Member

Posts: 2519
Joined: 11-Mar-2017
Last visit: 02-Dec-2021
Location: 🌎
Thanks Jagube.

One of the participants wrote a general audience press article on their experience:

https://www.vice.com/en/...esearch-salvinorin-a-mri
 
Spiralout
#4 Posted : 1/27/2021 2:33:37 PM

DMT-Nexus member


Posts: 584
Joined: 13-Dec-2013
Last visit: 02-Dec-2021
This doesn't surprise me. I imagine it's more a function of a novel shift in perception more than it is the chemical or activity that acts as a catalyst.
 
changaforchange
#5 Posted : 1/27/2021 3:10:08 PM

changaforchange


Posts: 123
Joined: 16-Oct-2016
Last visit: 07-Nov-2021
Location: space
thanks for this... I am actually taking Andrew Gallimore's Psychedelics and the Brain Master Course as we speak and it is touching the DMN towards the end.

quite interesting and useful stuff.
changa is my medicine
 
 
Users browsing this forum
Guest

DMT-Nexus theme created by The Traveler
This page was generated in 0.014 seconds.