CHATPRIVACYDONATELOGINREGISTER
DMT-Nexus
FAQWIKIHEALTH & SAFETYARTATTITUDEACTIVE TOPICS
Injury-Triggered Blueing Reactions of Psilocybe “Magic” Mushrooms Options
 
Loveall
#1 Posted : 12/1/2019 9:18:04 PM

💖

Chemical expertSenior Member

Posts: 1805
Joined: 11-Mar-2017
Last visit: 09-Aug-2020
Location: 🌎
Article attached.

It seems like they identified an enzyme (PsiL) that oxidizes the -OH group, and after that dimers form, followed by dimers and larger groups.

Interested in any opinions. I believe some of these dimers had been proposed before (I remember endlessness mentioning them in chat). I think this is the first time they are verified (?). Cheers.
“... (a) psychedelic substance occasionally causes psychotic behaviour in people who have not taken it.”
Excerpt from a McKenna talk transcript / audio.
 

Trippy glass for trippy people.
 
downwardsfromzero
#2 Posted : 12/1/2019 10:35:16 PM

No way ticket

Chemical expertSenior Member

Posts: 4936
Joined: 30-Aug-2008
Last visit: 07-Aug-2020
Location: square root of minus one
Great that they've confirmed the structure I suggested - not necessarily to the scientists involved - 12 years ago Big grin (I have evidence!) and the enzymology ices the cake nicely.

Quote:
dimers form, followed by dimers and larger groups.
*trimers, tetramers. With the higher oligomers they've taken the idea further than my suggestion. It's not unexpected to see that the additional cross-linking takes place in the positions they found.

All-in-all, a good piece of work that answers a long-standing question.

The attached structures were drawn in 2007. (It's the 5,5-dimer that forms first and cross-linking occurs in the 2 and 7 positions, using the conventional tryptamine numbering scheme. The numbering scheme used in the paper is different as it was more convenient for their C-13 NMR study of the dimerisation kinetics.)
downwardsfromzero attached the following image(s):
2dimer.jpg (10kb) downloaded 30 time(s).
5dimer.jpg (10kb) downloaded 29 time(s).
7dimer.jpg (10kb) downloaded 29 time(s).
Ora, lege, lege, lege, relege et labora

“There is a way of manipulating matter and energy so as to produce what modern scientists call 'a field of force'. The field acts on the observer and puts him in a privileged position vis-à-vis the universe. From this position he has access to the realities which are ordinarily hidden from us by time and space, matter and energy. This is what we call the Great Work."
― Jacques Bergier, quoting Fulcanelli
 
 
Users browsing this forum
Guest

DMT-Nexus theme created by The Traveler
This page was generated in 0.012 seconds.