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Piperine Options
 
Cactus Man
#1 Posted : 6/3/2018 5:00:47 AM

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Been experimenting with extracting piperine from black pepper recently. About to get a nice yield off 100g. What is the recommended dosage of this stuff?
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blue.magic
#2 Posted : 6/3/2018 1:01:22 PM

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I've read something like 5 - 20 mg per day just by quick googling.

20 mg of piperine is say to increase bioavailability of curcumine 15-fold so this amount seems to already strongly blocks the digestive enzyme.

BTW have you watched the NileRed's piperine extraction video? He seems to be able to make quite pure product:

 
Cactus Man
#3 Posted : 6/3/2018 4:13:32 PM

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I guess ill start with about 10mg to be safe. Thanks for the reply!
"If you do not posses the ashes you will not be able to obtain our salt and without our salt you will not be able to impart to our substance a bodily form for the coagulation of all things is produced by salt alone." ~ Basil Valentine
 
Cactus Man
#4 Posted : 12/6/2018 12:18:32 AM

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After putting it off for a really long time I am finally finishing up my first successful small scale piperine extraction!

Right now I am freeze precipitating the end product. Planning to try to use it in about a 10mg dose as a booster for kratom tomorrow as I hear it potentiates kratom quite well!

Anyone know of other things piperine can be used to potentiate? I have high hopes for this compound! Thumbs up
"If you do not posses the ashes you will not be able to obtain our salt and without our salt you will not be able to impart to our substance a bodily form for the coagulation of all things is produced by salt alone." ~ Basil Valentine
 
benzyme
#5 Posted : 12/6/2018 1:23:50 AM

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https://en.m.wikipedia.org/wiki/CYP3A4

look under Ligands.
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Cactus Man
#6 Posted : 12/7/2018 2:24:01 AM

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benzyme wrote:
https://en.m.wikipedia.org/wiki/CYP3A4

look under Ligands.


thanks man! ill get back to you all soon on how some of my personal experiments with it go!

decided to do some cactoos today instead and skipped the piperine.

gonna check up on it in the freezer soon to see if it precipitated. Thumbs up
"If you do not posses the ashes you will not be able to obtain our salt and without our salt you will not be able to impart to our substance a bodily form for the coagulation of all things is produced by salt alone." ~ Basil Valentine
 
 
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