I believe my experiences with drugs have made me a better person, more mature and more perceptive. Far more often I am now able to free my mental energy to gain insight.

marijuana - pain and stress relief, makes me calm and reflective.
mdma - love, intimacy
2cx, lsd - insight into the nature of perception
psilocybin, dmt - to become reconciled with the natural world and the nature of consciousness

all of the above have helped me deal with physical pain that I have been in the last two years.

Alcohol - nothing like a good beer at the end of a hard day's work. Sometimes, when the time's right, I'll have 3-4 beers to loosen social inhibitions and have a good time with friends. A glass of proper wine and a good book also go very well together, I find.

Cannabis - occasionally - for insights, meditation, self-reflection, and a good night's sleep. I do find it interferes with dreams, which seem to offer much information to the conscious self, so "everything in moderation".

Acid - I use it occasionally, I find it tends to "land in my lap" at the right times, so I don't go out of my way for it. As Tom Wolfe said, "intellectuals soar on the stuff". To fly, mentally, physically, essentially.

Mescaline - I find this is great for being in the nature, with the Great Sky above, trees around, a gentle breeze.

I use drugs because I am human.

My personal reasons include insight, growth, spirituality, pleasure, euphoria, pain management, appetite stimulation and communication enhancement. My list of substances and activities is long, though some, like alcohol I use extremely infrequently.

I have my issues and still need a job but I feel more fully plugged into every single breath of every moment of my life than ever before. I quit taking drugs to "escape" life years ago. He he, unless you count my heavy reading addiction along these lines.