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Mescaline, DMPEA (Potential MAOI), Tyramine GC-MS Analysis Options
 
Innocent
#1 Posted : 2/8/2019 2:37:45 AM

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Hey guys

DMPEA has been confirmed as frequently occurring in echinopsis pachanoi and has MAOI properties - oddly prevents breakdown (in rat brains) of tyramine but not as much for tryptamines https://sci-hub.tw/https...g/10.1002/jps.2600660741

Interestingly, tyramine has been found in echinopsis pachanoi too. Tyramine + MAOI sounds dangerous, but this issue doesn't seem to occur in reality when people consume the cacti.

I was trying to work out how much DMPEA is likely contained in echinopsis pachanoi compared to mescaline.

Came across this study https://www.sciencedirec...le/pii/S0378874110004836

Full paper here: http://sci-hub.tw/https:...0.1016/j.jep.2010.07.021

On page 4 there is a graph (attached) of the GC–MS.

If the molecular mass of mescaline is 211, then why is there a peak at 181 that's treated as mescaline in the paper?

If 181 is assumed to be mescaline, how is this not confused with DMPEA (mass 181) which is also contained in extracts of echinopsis pachanoi?

My assumption is the levels of DMPEA and tyramine must be very low, with some preparations containing no detectable DMPEA.
Innocent attached the following image(s):
gcms tpach.PNG (205kb) downloaded 60 time(s).
 

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endlessness
#2 Posted : 2/8/2019 10:01:51 AM

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Hey friend!

Thanks for posting aobut this interesting subject!

I was also interested in this and went over all of the publications released on cactus analysis I could find and summed it up in the first post here: https://www.dmt-nexus.me...aspx?g=posts&t=71353

As you can notice, whenever numbers are quoted for DMPEA, they are actually really small/trace quantities, so your assumption is pretty much right Smile
 
Innocent
#3 Posted : 2/10/2019 3:14:49 AM

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That is a very comprehensive post, solid work!
 
 
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