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Effects of Exercise on Dopamine Neurotransmission in Parkinson’s Disease Options
 
tatt
#1 Posted : 4/4/2018 8:32:21 PM

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https://www.ncbi.nlm.nih...pmc/articles/PMC4621077/
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do zavtra

 

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Ulim
#2 Posted : 4/4/2018 8:49:01 PM

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https://en.wikipedia.org/wiki/Pergolide
There is also lsd for parkinsons Wink
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tatt
#3 Posted : 4/5/2018 11:13:01 AM

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Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940446/




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do zavtra

 
Cognitive Heart
#4 Posted : 4/5/2018 2:27:57 PM

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Excellent post. Thanks, tatt! Smile
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Aum_Shanti
#5 Posted : 12/16/2018 11:40:31 AM
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In this respect maybe also interesting some of the history of its usage for PD, which is indicated in this paper ("Banisteriopsis caapi, a Forgotten Potential Therapy for Parkinson’s Disease?" ).

(see attached doc)
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Bancopuma
#6 Posted : 12/17/2018 3:13:40 PM

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Interesting stuff. The positive effects of exercise are likely due, at least in part, to the effect of exercise on modulating levels of neuronal growth factors, such as glial cell-derived neurotrophic factor (GDNF) which promotes the survival and differentiation of dopaminergic neurons, the neurons lost during the progression of Parkinson's disease. Direct GDNF brain infusions have shown potential but this is obviously a pretty invasive approach.

As well as exercise, it seems like iboga(ine) may be also promising in treating Parkinson's disease, as it has been found to cause a long-term increase in GDNF expression via a positive feedback loop. I made this link a while back, and interestingly recently met and spoke to someone from the Beckley Foundation who is planning to conduct research on this.

https://www.dmt-nexus.me...aspx?g=posts&t=13217
 
 
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