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Supercritical CO2 for the Entheogenic Hobbyist Options
 
benzyme
#101 Posted : 10/14/2015 5:20:36 PM

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here are a couple of good reads on the subject, from my dropbox

https://www.dropbox.com/...28bookfi.org%29.pdf?dl=0
https://www.dropbox.com/...28bookfi.org%29.pdf?dl=0

for those that missed it, here is the complete parts list
https://www.dmt-nexus.me...&m=678821#post678821

that's what I used to put together a reliable SFE, to safely handle pressure up to 124 bar (1800 psi).
(note: all connections on the high-pressure side should be consistently sized, i.e. 1/4" NPT throughout. don't use reducing/enlarging adapters).

the 1000cc sample cylinder can probably hold a half-kilo of dried plant material.

"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
 

STS is a community for people interested in growing, preserving and researching botanical species, particularly those with remarkable therapeutic and/or psychoactive properties.
 
benzyme
#102 Posted : 10/17/2015 7:28:11 AM

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https://www.researchgate...f50fe964609129000000.pdf

for dealing with free base alkaloids, see page 7 (pp. 420)
"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
 
Jees
#103 Posted : 10/17/2015 10:57:00 AM

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Thank you for sharing the links B.
Though some texts are hard to wrap my non chemist head around Pleased

Instead of increasing the polarity of CO2 to get the alkaloid salts in plant matter, we might beforehand mix plant material with a base, wet, then dry, like is done in the dry-teks, and work with pure CO2 without polarity modifier?
 
benzyme
#104 Posted : 10/17/2015 2:27:09 PM

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it really depends on the overall polarity of the molecule. in the case of DMT, a polar entrainer probably isn't necessary, whereas with mescaline, it would be advised.

I'd add KOH in methanol, to do a basification of the dried plant material, prior to applying the supercritical CO2. the SS sample cylinder and collection vessel can handle strong base with no issues.

or, if the basification is done as you mentioned, 95%ethanol added with the SC-CO2.
again, this is necessary for some of the more polar alkaloids, ones which contain functional groups containing oxygens (hydroxy, methoxy groups, etc,)
"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
 
benzyme
#105 Posted : 10/25/2015 5:08:10 AM

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ok, so I've run 5 experiments so far, four on pecans, one on 75 dried ghost peppers with everclear as the entrainer.
no issues except for very small leaks twice, this is due to improper taping/swaging (tightening)

The tank needed 60C to maintain 1100-1150 psi in the latter extraction done most recently. mind you, this is a 10lb cylinder.

thus, it would behoove one to use a storage tank with a siphon (the guys at the gas supply shops call it a diptube) installed.
this will allow you to get the most use out of your tank. I took my original 20# tank to get one installed.
"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
 
benzyme
#106 Posted : 10/27/2015 2:58:43 PM

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I don't know exactly what freeze precipitated out, but it doesn't look very nice Twisted Evil

next on the to-do list, san pedro. stay tuned..
benzyme attached the following image(s):
image.jpg (1,336kb) downloaded 203 time(s).
"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
 
Rivea
#107 Posted : 7/23/2018 2:32:08 AM

No.. that can't be...

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I know that this is an old thread, but because I am trying to do this I am reading all threads here. I want to compliment you Benz for all of the work you have presented here and the personalized help you have given me. I have all sorts of goodies coming here to start experimenting with this in the coming weeks.
Everything mentioned herein has been deemed by our staff of expert psychiatrists to be the delusional rantings of a madman who has been treated with Thorazine who is hospitalized within the confines of our locked facility. This patient sometimes requires the application of 6 point leather restraints and electrodes at the temples to break his delusions. Therefore, take everything mentioned above with a grain of salt...
 
benzyme
#108 Posted : 7/23/2018 3:17:42 AM

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Big grin thanks, and no problem.
I got very nervous the first couple of runs, but I “designed” it to be very safe.
Put over 20 extractions on it, with no issues other than small leaks due to improper taping.
"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
 
Rivea
#109 Posted : 7/29/2018 4:57:10 PM

No.. that can't be...

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I understand the nervousness. When I first starting building 'dangerous things' I was nervous at first too. I learned that thinking through every little detail and double checking everything is essential. I find that that process allows me to think of every assembly detail and remember it... all things properly tightened, sealants applied, gaskets installed, voltages correct, and more. I first started with building vacuum tube amplifies in the mid 1970's. The first ones started with 150 volt power supplies and the last one had almost 600 volts at 1 amp available speaking of dangerous. Then it was building at the time high horsepower V8 engines up to 400 horsepower. I have built from the bottom end up about 8 engines and all have lived for more than a decade before having to tear them down again. Each and every detail needs appropriate attention. In this case it is all high pressure plumbing operation at 1800 PSI or so. Teflon tape sealant are to be applied everywhere, all joints tightened appropriately, lower test pressures (175 PSI) applied and leak checking will be done before putting the system to its full pressure. It's better to be a little nervouse and cautious than risk life and limb.
Everything mentioned herein has been deemed by our staff of expert psychiatrists to be the delusional rantings of a madman who has been treated with Thorazine who is hospitalized within the confines of our locked facility. This patient sometimes requires the application of 6 point leather restraints and electrodes at the temples to break his delusions. Therefore, take everything mentioned above with a grain of salt...
 
benzyme
#110 Posted : 9/2/2019 1:33:14 PM

analytical chemist

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'twas asked if I've ever successfully extracted DMT with a SC-CO2 extraction.

No.

there are a couple reasons I never attempted it: in plant cells, it is observed/theorized that DMT exists as a tannate salt. To extract it out of cells, and break that salt bond, we use acid/base, or base extractions. Neither acid nor base is used in SFE.
Hypothetically, ethanol may be used as an entrainer solvent with CO2, to pull from MHRB powder. The caveat is that CO2 is very effective at pulling plant lipids and oils. Whatever is pulled, will need to be cleaned with liquid-liquid extraction (sep funnel workup).

can it be done? perhaps... but not as effectively/efficiently and quickly as an A/B extraction.
"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
 
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