DMT-Nexus member
Posts: 574 Joined: 24-Jan-2009 Last visit: 25-Aug-2023 Location: somewhere in the sands of time
|
New hallucinogenic plant discovered: Zanthoxylum sp. rootbark usage among Brazilian quilombolas Quote:An anthropologist reported to me that Brazilian quilombolas, probably located in the state of Santa Catarina, are smoking Zanthoxylum sp. rootbark ( the species in the picture ). They do this so that they can obtain mild hallucinogenic effects.
He told me that they take young plants off the ground entirely, and then proceed to smoke their rootbark.
DMT has already been detected in the leaves of Zanthoxylum arborescens. Now, it seems that maybe a blend of DMT and other alkaloids is also present in the rootbark of such Zanthoxylum plants. https://42e54.wordpress....g-brazilian-quilombolas/
|
|
|
|
|
DMT-Nexus member
Posts: 574 Joined: 24-Jan-2009 Last visit: 25-Aug-2023 Location: somewhere in the sands of time
|
https://www.researchgate..._Zanthoxylum_arborescensOld and new alkaloids from Zanthoxylum arborescens Quote:The new alkaloids (2S,5S)-2,5-dibenzyl-1,4-dimethylpiperazine, 8-hydroxy-4,7-dimethoxyfuranoquinoline, and 8-isopentenyloxy-4,7-dimethoxyfuranoquinoline were isolated from Zanthoxylum arborescens (Rutaceae). The β-D-glucopyranoside of hordenine (previously known only as a synthetic) was also found. The known alkaloids skimmianine, tembetarine, hordenine, N,N-dimethyltryptamine, N-methyltryptamine, 1-methyl-3-(2′-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2′-(4″-methoxyphenyl)ethyl]-1H,3H-quinazoline-2,4-dione also were isolated. Structure proof of the two new furanoquinoline alkaloids necessitated a revision in the previously suggested structure for perfamine, a cyclohexadienone alkaloid from Haplophyllum perforatum. Wikipedia: Zanthoxylum arborescens, DMT in leaves Zanthoxylum procerum, DMT in leaves
|
|
|
DMT-Nexus member
Posts: 989 Joined: 27-Dec-2014 Last visit: 17-Feb-2024
|
Hmmm... I wonder what other alkaloids are present, if any, and what kind of DMT percentages it has. Wasn't much info in the article. Thanks for the find though Edit: never mind you posted before I did,lol.
|
|
|
DMT-Nexus member
Posts: 574 Joined: 24-Jan-2009 Last visit: 25-Aug-2023 Location: somewhere in the sands of time
|
Different species it seems though. First article doesn't specify the species.
|
|
|
DMT-Nexus member
Posts: 14191 Joined: 19-Feb-2008 Last visit: 16-Apr-2024 Location: Jungle
|
Sounds interesting, thanks for sharing Though the lack of sources ("an anthropologist told me" ) is unnerving. And just one pic of the trunk....
|
|
|
DMT-Nexus member
Posts: 2889 Joined: 31-Oct-2014 Last visit: 03-Nov-2018
|
http://www.scielo.br/sci...=S0100-40422012001100013Alkaloids of root barks of Zanthoxylum spp Sandra Virgínia Alves HohlemwergerI; Edijane Matos SalesI; Rafael dos Santos CostaI; Eudes da Silva VelozoI,*; Maria Lenise da Silva GuedesII IDepartamento do Medicamento, Faculdade de Farmácia, Universidade Federal da Bahia, Rua Barão de Jeremoabo, s/n, 40170-115 Salvador - BA, Brasil IIHerbário Alexandre Leal Costa, Instituto de Biologia, Universidade Federal da Bahia, Rua Barão de Jeremoabo, s/n, 40170-115 Salvador - BA, Brasil http://www.scielo.br/sci...=S0100-40422012001100013Quote:The investigation of hexane and methanol extracts of the root bark of Z. rhoifolium and Z. stelligerum also investigated showed the presence of alkaloids dihydrochelerythrine, anorttianamide, cis-N-methyl-canadine, 7,9-dimethoxy-2,3-methylenedioxybenzophenanthridine and angoline -eg
|
|
|
DMT-Nexus member
Posts: 2889 Joined: 31-Oct-2014 Last visit: 03-Nov-2018
|
https://www.dmt-nexus.me...;t=72978&find=unreadThis thread is regarding the exact same topic... -eg
|
|
|
DMT-Nexus member
Posts: 2889 Joined: 31-Oct-2014 Last visit: 03-Nov-2018
|
The other link specifically mentions Zanthoxylum rhoifolium rootbark...
-eg
|
|
|
DMT-Nexus member
Posts: 3090 Joined: 09-Jul-2016 Last visit: 03-Feb-2024
|
Quinoline's..don't they normally counteract the effects of DMT?
|
|
|
DMT-Nexus member
Posts: 2889 Joined: 31-Oct-2014 Last visit: 03-Nov-2018
|
Quote:The new alkaloids (2S,5S)-2,5-dibenzyl-1,4-dimethylpiperazine, 8-hydroxy-4,7-dimethoxyfuranoquinoline, and 8-isopentenyloxy-4,7-dimethoxyfuranoquinoline were isolated from Zanthoxylum arborescens (Rutaceae) The β-D-glucopyranoside of hordenine (previously known only as a synthetic) was also found. The known alkaloids skimmianine, tembetarine, hordenine, N,N-dimethyltryptamine, N-methyltryptamine, 1-methyl-3-(2′-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2′-(4″-methoxyphenyl)ethyl]-1H,3H-quinazoline-2,4-dione also were isolated. Structure proof of the two new furanoquinoline alkaloids necessitated a revision in the previously suggested structure for perfamine, a cyclohexadienone alkaloid from Haplophyllum perforatum. So Zanthoxylum arborescens contains: hordenine, N,N-dimethyltryptamine, N-methyltryptamine? We're these alkaloids quantified? (2S,5S)-2,5-dibenzyl-1,4-dimethyl-piperazine interests me as well, I attempted to depict this molecule, but may not have done it properly, if I made a mistake please correct me. I wish I could get Full text access to this article.... (2S,5S)-2,5-dibenzyl-1,4-dimethylpiperazine, 8-hydroxy-4,7-dimethoxyfuranoquinoline, and 8-isopentenyloxy-4,7-dimethoxyfuranoquinoline are all fascinating in their own rights, I have particular interest in the piperazine compound as piperazine compounds possess a vast range of pharmacological properties, there are piperazine compounds which are Antianginals, Antidepressants, Urologicals (like Viagra), Antihistamines, Antiserotonergics, Antipsychotics, and even Recreational Drugs, so this interests me... But then: The β-D-glucopyranoside of hordenine, skimmianine, tembetarine, hordenine, N,N-dimethyltryptamine, N-methyltryptamine, 1-methyl-3-(2′-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2′-(4″-methoxyphenyl)ethyl]-1H,3H-quinazoline-2,4-dione I mean the quinazoline and phenethylamine compounds were a intriguing, but the big shocker was N,N-dimethyltryptamine, N-methyltryptamine... There were reports of plants of this species being smoked as an intoxicant, mentioned in this thread: https://www.dmt-nexus.me...;t=72978&find=unread however these were specific to Zanthoxylum rhoifolium rootbark, I have done my best to locate chemical analysis of these species, though as of now nothing as interesting as the chemical profile listed for Zanthoxylum arborescens... Zanthoxylum arborescens appears to have actual Entheogenic potential, while Zanthoxylum rhoifolium does not look as promising, yet Zanthoxylum rhoifolium was reported in the link above as being smoked Brazilian "quilombolas"... -eg entheogenic-gnosis attached the following image(s): KINDLE_CAMERA_1478157489000.jpg (246kb) downloaded 176 time(s).
|
|
|
DMT-Nexus member
Posts: 2889 Joined: 31-Oct-2014 Last visit: 03-Nov-2018
|
dragonrider wrote:Quinoline's..don't they normally counteract the effects of DMT? Quinoline and Isoquinoline compounds can be found in mescaline producing cacti, as well as opium poppies... Most people seem confused that shulgin wrote "The Simple Plant Isoquinolines", they speculate on creating psychedelic molecules based off of quinoline or isoquinoline molecules, Which is a mistake, this was NOT the point, and I doubt there's very much of interest in that area. Shulgin explained that his interest here had to do with their occurrence in both mescaline producing cacti as well as opium poppies, he admits that they are not pharmocologically interesting, he saw them as "side products" in two "narcotic" plants, which in itself made them interesting, I don't think he wanted to alter these molecules to mimic psychedelic molecules, and I don't think he cared about their pharmacology. The Simple Plant Isoquinolines by Alexander shulgin I don't know very much about these compounds, so I'll stop here. https://www.scribd.com/m...inoline-and-Isoquinoline-eg
|
|
|
DMT-Nexus member
Posts: 3090 Joined: 09-Jul-2016 Last visit: 03-Feb-2024
|
Yeah, i think they're partly responsible for the foggy feeling that sometimes come with peyote and san-Pedro experiences. One of the reasons why pure mescaline is just so much better (in my opinion) than peyote or torches.
|
|
|
Boundary condition
Posts: 8617 Joined: 30-Aug-2008 Last visit: 16-Apr-2024 Location: square root of minus one
|
entheogenic-gnosis wrote:Quote:The new alkaloids (2S,5S)-2,5-dibenzyl-1,4-dimethylpiperazine, 8-hydroxy-4,7-dimethoxyfuranoquinoline, and 8-isopentenyloxy-4,7-dimethoxyfuranoquinoline were isolated from Zanthoxylum arborescens (Rutaceae) The β-D-glucopyranoside of hordenine (previously known only as a synthetic) was also found. The known alkaloids skimmianine, tembetarine, hordenine, N,N-dimethyltryptamine, N-methyltryptamine, 1-methyl-3-(2′-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2′-(4″-methoxyphenyl)ethyl]-1H,3H-quinazoline-2,4-dione also were isolated. Structure proof of the two new furanoquinoline alkaloids necessitated a revision in the previously suggested structure for perfamine, a cyclohexadienone alkaloid from Haplophyllum perforatum. So Zanthoxylum arborescens contains: hordenine, N,N-dimethyltryptamine, N-methyltryptamine? We're these alkaloids quantified? (2S,5S)-2,5-dibenzyl-1,4-dimethyl-piperazine interests me as well, I attempted to depict this molecule, but may not have done it properly, if I made a mistake please correct me. That's the diphenyl compound you've drawn, the benzyl group has a methylene spacer. Will post structures later. Quote:I wish I could get Full text access to this article.... There's a thread for scientific paper requests Merge with this thread? Quote:however these were specific to Zanthoxylum rhoifolium rootbark, I have done my best to locate chemical analysis of these species, though as of now nothing as interesting as the chemical profile listed for Zanthoxylum arborescens...
Zanthoxylum arborescens appears to have actual Entheogenic potential, while Zanthoxylum rhoifolium does not look as promising, yet Zanthoxylum rhoifolium was reported in the link above as being smoked Brazilian "quilombolas"...
-eg
The ethnomedicinial use of Zanthoxylum species has been examined to some extent. Isn't Z. arborescens used for treating toothache? “There is a way of manipulating matter and energy so as to produce what modern scientists call 'a field of force'. The field acts on the observer and puts him in a privileged position vis-à-vis the universe. From this position he has access to the realities which are ordinarily hidden from us by time and space, matter and energy. This is what we call the Great Work." ― Jacques Bergier, quoting Fulcanelli
|
|
|
DMT-Nexus member
Posts: 2889 Joined: 31-Oct-2014 Last visit: 03-Nov-2018
|
Your right downwardfromzero, it should have been depicted as in the picture below, which shows benzyl VS phenyl. -eg entheogenic-gnosis attached the following image(s): phenyl-vs-benzyl.jpg (50kb) downloaded 135 time(s).
|