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lophophora williamsii and harmala alkaloids Options
 
entheogenic-gnosis
#1 Posted : 3/21/2016 11:15:54 AM
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Say that, hypothetically, I have 3 dried lophophora williamsii buttons, the buttons are only 1-1.5cm across, but also have about 1-2 inches of carrot like root connected.

The three buttons are long dead, but we're not badly damaged and are still green...

There's no way there's sufficient mescaline content in such a small quantity...

Now, hypothetically, if one we're to inhibit their monoamine oxidase via peganum harmala seeds, would this minor quantity be effective in producing even mild psychedelia?

Quote:
with 100 mg harmaline, 60 mg mescaline (3,4,5-trimethoxyphenethylamine) [20 min]) "At two hours I was in a pleasant state of physical relaxation, a fine sense of well being, and I found music most enjoyable. From then to the fourth hour, thoughts flowed freely, and it became obvious that insight was a major part of this experience. Normally unconscious thoughts were easily available. It was as if I could observe my mind in operation, as facts were weighed to form conclusions. By the sixth hour music was a thing of beauty, with the higher notes crisp and clear. The harmaline has probably worn off. Sleep at eight hours, and the next day was without any adverse effects. This was a remarkable experience, the insight of TMA, and the relaxation of MDMA."

(with 150 mg harmaline, 100 mg mescaline [15 min]) "A stomach ache developed at about 45 minutes, followed by a mild nausea which occurred intermittently throughout the next six hours. I felt comfortable, although there was a slight discoordination at about two hours. Walking was never a problem but did require more concentration than normal. Colors on the television were obviously more intense, and highly saturated at this point and moderate photophobia developed. Even a fire in the fireplace was distracting, and stereo was best enjoyed in the dark. Attempts at sleep did not work until the ninth hour. Upon awakening there was a feeling of dehydration but otherwise no ill effects. Mild looseness of stools was present later that morning. Since experiments using only mescaline at doses between 80 and 120 mg resulted in no CNS effects at all, it seems clear that the MAO blocking effects of the harmaline were crucial to this experience.
it seems clear that the MAO blocking effects of the harmaline were crucial to this experience.
Shulgin; TIHKAL; harmaline entry


My research has convinced me of the relative safety of this MAOI/phenethylamine combination, in every other case involving phenethylamine or alpha-methyl-phenethylamine compounds I would strongly advise against an MAOI combination, though in the case of mescaline it appears to be safe...

(I'm aware there is more than just 3,4,5-trimethoxy-phenethylamine present in the buttons)

-eg
 

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