Although I've done 5-meo, all of the following, of course, is just my opinion:
Start in the 2-5 mgs range, especially for freebase.
Work your way up over a period of days/nights, mg by mg. For each increased mg, if you are anything like me, you will notice new, more intense effects.
Be ready for a much longer trip than NN, like 1-2 hours total.
Big doses are in the 15-25 mgs range. Be very very careful here, it's easy to get into trouble or to have a difficult/impossible to remember "white out." 5-meo-requires very advanced tripping skills
I find that if I do not utterly surrender I am hit with grotesque physical symptoms like deep groaning and drooling. I haven't purged on it but felt like I was coming close. I recommend keeping a purge bucket and water handy.
Don't expect a visual trip from 5-meo. Be ready to note feelings rather than visions.
I hope you enjoy it. To be honest, few do.
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