I think I've accidentally stumbled onto my answer before but I forgot WHY/HOW exactly freeze precip works I know some alkaloids do and some don't. I tried searching google, and couldn't find anything so I was hoping someone could explain why exactly this works on some alkaloids, and how I can find out if certain alkaloids will freeze precip so I can experiment further on my own in the future. So can someone please explain the process of how I can tell if an alkaloid will freeze precip or not, and why exactly this happens with some? I kinda know the answer it obviously has to do with some chemicals losing solubility in cold substances, however, is there anything else to it? Mostly though I want to know how to find out if this is useable for particular alkaloids.

It has to do with the warmer solvent dissolving more of the alkaloid... like the same amount of hot water dissolves more salt than cold water. If you were to cool that water... salt would precipitate as it cooled.

So goes it with DMT/Naptha.

I pointed out I knew that much thank you though, like I said I'm mostly looking for how to figure out which alkaloids will precip for instance I know DMT will freeze prcip out of naphtha but Harmalas won't.... why is that and how would I figure out like is there some info on the alkaloid and the solvent type I can compare to figure out which ones will/won't does that make more sense?

https://www.dmt-nexus.me...amp;m=450723#post450723

Unfortunately there is no such thing as a selective solvent.

also important thing to note is that, more polar solvents will pull bigger spectrum of substances(in the case of dmt extraction, more crap), and non polar solvents tend to pull less.

so, by changing the polarity of certain solvents or solvent mixtures we can make for some substances/alkaloids to precipitate. this is how i understand it works.