Does making a tea remove trich toxins? Options
#1 Posted : 1/23/2021 4:43:51 PM

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The toxins found in Trichoderma longibrachiatum, trilongins, are peptides.

From :

Peptides shorter than five residues are usually soluble in water or aqueous buffer, except when the entire sequence consists of hydrophobic amino acids (e.g., W, L, I, F, M, V, Y)

Trilogins are 11-residue and 20-residue peptaibols and it seems most of the amino acids in them are hydrophobic.


These were identified by LC/MS as one 11-residue and eight 20-residue peptaibols, AcAib-Asn-Leu/Ile-Leu/Ile-Aib-Pro-Leu/Ile-Leu/Ile-Aib-Pro-Leuol/Ileol (1175 Da) and AcAib-Ala-Aib-Ala-Aib-Ala/Aib-Gln-Aib-Val/Iva-Aib-Gly-Leu/Ile-Aib-Pro-Val/Iva-Aib-Val/Iva/Aib-Gln/Glu-Gln-Pheol(1936–1965 Da) (Aib, α-aminoisobutyric acid; Ac, acetyl; Ileol, isoleucinol; Iva, isovaline; Leuol, leucinol; Pheol, phenylalaninol).

So if you have fungal matter (e.g. myceliated grain) contaminated with trich, making a tea would seem to reduce the amount of toxins if any are present?

Of course you don't want to eat trich when you know it's there, but if you can't see it and you're going to eat it anyway, tea would seem to be preferable to eating.

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