I recently received some San Pedro and plan on ingesting it but I am not sure which tek to use and I also have a few questions. I stumbled upon this resin tek which seems promising but there is so much controversy going on in the thread. I tried reading through some of it but the whole thread is very long and I cannot find any conclusions. House says how great the tek is, then 69ron says that it's not that good unless you're careful because heat tends to destroy mescaline, yet I have read in some places that mescaline is a very "hardy molecule" and that it is quite heat-resilient. I am wondering why did House, Jorkest, and 69ron decide to go at it for so long (the thread is 20 pages long!)
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Anyway, here are my questions:

How sensitive is mescaline to heat?
What is the consensus nowadays on resin?
Which tek is recommended nowadays?
Why does House's tek call for a maximum of 5 hour's of boiling specifically
Does it really help to freeze-thaw in house's method?
Is it really only worth it to use the green skin? (I have read the white flesh can contain 1/3 of mescaline of the complete cactus)

Boiling temps are fine-- people have pressure-cooked it (usually reaches ~250 degrees F) with no problems at all. Higher than that, you may or may not ruin it.

It is the boiled off matter minus water. It works, and lots of people like it just fine.

Still a spectrum of answers. I boil and reduce. Won't bother extracting. Others extract, and others powder and eat. Your preference for the amount of work you want to put in to the result matters, not the quality of the TEK-- they're all there because they all work. If you want crystal extract, you must extract. If you can't stomach the reduced (and filtered) cactus juice, you might be better with resin. It's really how much work YOU want to do, not whether there is a *better* method.

No idea-- in my experience it's not long enough-- but I only use vinegar and water, so it's not his TEK. When I boil I aim for 24 total hours at simmer temp (over 2 days usually), but his TEK is respected-- follow and trust your chosen TEK.

The reason is to break open cells when they freeze-- it is not necessary but it *could* help. Hard to prove one way or another. I don't bother myself. Others do.

I've used both-- I default to using all of it myself, but I have a big pot with plenty of space for 2+ feet to easily fit in sliced very thin. I've never read that it's a third in the core, I've heard much less than that-- but I boil everything because why wouldn't you-- UNLESS your chosen TEK indicates the preference-- Follow the TEK.

Proof I would bring to the table on whether freeze/thaw is worth the effort would be to give it a try and watch how much juice appears in the container over 3 or so freezes. Definitely worth it.

Mescaline is not very sensitive to heat.

If you choose way of resin, I recommend you to make water extracted resin, then to dissolve it in some strong ethanol (like 80%), filter and evaporate ethanol.

The main hassle in cactus preparation is slimy mucilage, you need quite long boiling time, or strong base to destroy it. Freezing and thawing is one way how to help yourself with it, but it is not necessary.

White flesh contains some mescaline, but most of it is in green part. Your choice depends mainly on amount of cactus available. If you have plenty of it, use just green flesh.

Thanks all for the thorough replies!

I was mainly talking about this post in which AlbertKLloyd mentions that the core/white flesh may contain up to 2/3's of the alkaloids!



Edit: A quick google search yielded this study, which mentions the location of the alkaloids in trichocereus terscheckii.

"Reti and Castrill6n (36) found 0.29 % total alkaloids in the green epidermis of Trichocereus terscheckii, while the central parts, including cortical parenchyma, contain 0.45 %". Indeed nearly 2/3's of the alkaloids

The thing about San Pedro is that you will find endless opinions about it and everyone is convinced that their way of doing it is best.

The most important factor is to start out with high quality cuttings. Nothing else matters as much as that.

I have had best results by simmering the tea for a long time (12 to 14 hours), and using the entire cutting, white flesh and all. When I have boiled the tea at high heat (full, raging boil) the tea still comes out potent, but it just feels like a little bit of the vividness is lost. Its kind of similar to mushrooms: the fresh shrooms just have a little something extra and more vivid compared to dried shrooms. Raw, uncooked cactus is similar in that way. It just has something a little extra to it. Full boil seems to diminish that for me, but with the gentle simmer it still seems to be there. But YMMV. Best luck.

Yep, everyone has their preferred method with cactus.

I leave in the core if there's room in the pot. If not, oh well. Although I normally freeze/thaw x 3 or 4 I've had perfectly good results with a quick brew of ~ 400 grams bridgesii, one hour fresh to tea, start to finish. Just de-spine, filet out the green, blender, simmer til the foam turns to liquid, filter with t-shirt and down the hatch. I doubt I'll ever do all of that extended simmering again.

My go-to now is extracted mescaline. I can handle the tea and purge fine but with extracted I've had no more than transient nausea and never purged. When extracting I always freeze/thaw multiple times but still only simmer for maybe 45 minutes or an hour.

My extraction method is STB using reduced tea, NAOH, D-Limomene and 5% Vinegar. It is easy, the resulting full spectrum acetate works well and can be capped up. It feels exactly like tea but is far easier to measure the dose.

I used this tek for guidelines on the relative amounts: https://wiki.dmt-nexus.m...ene_Mescaline_Extraction

Thanks everyone for the help so far!

I have a few more question's that are slightly related but I was not sure whether to start a new thread or not.

I stumbled upon this microwave tea tek which seems incredibly easy and fast, but I am wondering whether all of the mescaline would be released from flesh/skin using just the water that is already in the cactus, or whether I should add more water. Also, how long should I microwave the cactus? I was unable to find much info on people preparing tea with a microwave so I would appreciate any help.