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Passiflora incarnata as the MAOI component Options
 
twitchy
#1 Posted : 7/10/2019 10:09:52 PM

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I know there is, or at least has been, some debate about whether the MAOI properties of Passiflora come solely from the harmala alkaloids or in combination with the flavonoids, but I was wondering if a solid and practical consensus was ever reached as to an effective oral dosage for inhibiting MAO in the gut.
I've read through a lot of relevant material on here and the suggestions seem to range from 200 grams to a kilogram. I got the impression that the kilogram dosage was based on pure mathematics of the harmala content in P. incarnata. 1000 grams seems like a hell of a lot of material and I imagine that much passion vine would put an elephant to sleep long before it inhibited anything. That said, 1000 grams isn't much considering the growth rate though, hell I probably prune that much just trying to keep the vines from choking my other plants out every couple of days.
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Ferrum
#2 Posted : 8/5/2019 6:15:43 AM

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I've used 250 grams dry leaf from incarnata. It is very heavy on the tummy . I've wanted to refine it some but have nt .


I'm sure you can go lower , but I wouldn t go much , I'm a aya vine hardhead well maybe not too hard I like at least 100 gram vine as a starting area generally .

So 250 g passionflower is leaving a lot to be desired for me ....however caerulea passionflower is safe and has higher carboline percentage

So given that you could reduce the weight some .

I feel personally that it gives a better anti depressive effect to any aya like brew but if you don't have a strong stomach or can't refine it then i wouldn't think of letting it appeal to you

And yes a 1000 g of it is a lot of dry leaf

But it does grow fast in a season too

For a northern country vine to grow if you have a little backyard where no one cares I say grow it and use it if you can handle the gastrointestinal angst . And yeah you do prune that much and there are usable compounds in the stems as well

The fruit has as much as approximate 25 percent carboline s if you can them to fruit in some South American species and don't quote me but incarnata may as well. , in fact a popular aya like "wine " has been , and sometime s still is consumed in Brazil that contains passionflower fruit mashed , decanted , and "Jerma" "or hostilis bark added that I'm told tastes so delicious compared to true aya
 
twitchy
#3 Posted : 8/5/2019 8:45:29 AM

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Thanks for the reply. I wonder if anyone has tried a Manske type extraction on Passiflora teas, or this would even work?
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Ferrum
#4 Posted : 8/6/2019 1:02:46 AM

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No problem . that's a pretty simple one I'm sure it would help get rid of a lot of material

I'm sure it would work but you're going to get a lot of other compounds too .

Give it a shot and let us know , i have about 400 g of incarnata dried now I suppose I could but lol I'm so damn busy and have other projects . I'm positive it would work incarnata has been extracted before and harmalas isolated from it as early as the 1990s

There is a reference on erowid in the harmala area by three experiments ran with aya , rue and passionflower extracts smoked and it describes just that , the maoi nature of it and general areas of gram threshold s

It's pretty much confirmed and the general consensus and gram area ...myself included seems to be at least for incarnata about 200 to 300 sometimes 400 g dry leaf .

My experiences are with about 250 as I said , but I would go higher if I had to repeat it . I'd prob shoot for min 450 just for the power but threshold is prob 200 to 350 g
 
grollum
#5 Posted : 8/9/2019 9:15:13 PM

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I once drank a water extract / tea that I did out of 100g dried incarnata. I had no problems with the stomach and felt a quite strong stoned effect. But I didn't use it in combination so far,so can not speak about that.

One thing I asked myself is if it makes a difference which parts of the plant are used exactly. In general I think the whole plant above the ground is used , dried and drank as a tea.

The tea that I had, had also dried fruit bits in it which made the taste somehow quite strange and not enjoyable. Next time I try to drink only leaves.

Maybe only leaves are easier for the stomach?

I Have big hopes into the passiflora, since it is grow-able in many areas around the world.
 
twitchy
#6 Posted : 8/9/2019 9:34:38 PM

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I don't know if it's the case for just P. incarnata, but I I've read that that the MAOI components are most concentrated in the fruits and that at least some of the MAOI properties come from the flavonoids and other compounds. I wonder at what dosage specifically that it would become unsettling or nauseating, or even dangerous? It seems that the MAOI effects, subjectively at least, have been reported to last a couple days after consumption so it may not be entirely a reversible MAOI... but I'm guessing really.

Hell, a common temperate zone ayahuasca combination could be as big as the beginning of a new cultural enlightenment for Western Civilization. Considering our history over the last several hundred years, that may be overly optimistic. Crying or very sad
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