Thanks for the answers.
I dont find the tincture to be very bitter and I dont encounter problems taking it oraly.
I verified pictures of other Calea-plants that are the active ones, and my plant looks the same.
After this tincure is ready, I would like to make a resin.
I dont understand the non-polar or polar solvents extraction, what would be te difference?
If water extraction is possible too in terms of resin making, what would be the most appropriate method to make the best out of it?

Thanks Ufostrahlen,

I still wonder why a non polar would be more benficial than a polar solvent for Calea. But you are right; it is worth checking on that.
I would think, since the Indians made thea out of it, water being a polar solvent, that any polar solvent will do the trick.
How is your plant doing? Will you be making a tincture yourself?

Bob

Alright, I've read the paper again. The methanol extract is more potent than the hexane extract. However, both show activeness. What I mean is: why not make a full spectrum extract with both solvents. Maybe the non-polar compounds increase activeness of the polar compounds by a synergistic effect. The paper doesn't tell.

You can obtain it via sci-hub.org - search for: 10.1016/0378-8741(86)90002-4
If you are located in the US, use a proxy, otherwise the website won't work.

Or here:
http://www.researchgate....plant_Calea_zacatechichi

My plants are doing fine. I'm not sure if I'll make an extract. If I have mass amounts of leaves, I'll do. But if Ill end up with only 1 or 2 handfuls, I won't.

There are two varieties of plants on the market, the "bitter" strain (which is incredibly, incredibly bitter) and the "peppery" strain, they look identical for the most part but it's pretty easy to tell them apart by scent. The "peppery" strain smells very much like a tomato plant does, the bitter strain does not have this strong tomato-like scent coming off the plant, or really any scent at all. The majority of plants on the market are the "peppery" strain, afaik only one vendor carries live clones of bitter strains and they are hit and miss as to when they have them available. Most of the dried calea on the market is the bitter strain. People claim the peppery strain is also active, though personally it didn't work for me.

It's interesting that non-polar solvents pull an active product, this could be quite useful in cleaning it up.

Great info, thank you!