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How Do Plants Create DMT?

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Pyroprone

#1
Posted : 7/11/2019 12:15:18 AM

I've tried to do some searching but couldn't find the answer I was looking for.
Also sorry if there is a better place to post this.

My question is are there any studies or known science write ups on the actual process plants go through to create DMT? Not why it's present but how.

I'm curious because if the mechanism or process is known maybe we could play with said genes with crispr and CAS9. Or at least would be a interesting project.

benzyme

#2
Posted : 7/11/2019 12:47:43 AM

some people are already doing that.

and you’re just searching the wrong terms. You should be looking up Tryptophan biosynthesis and metabolism in plants.

https://www.ncbi.nlm.nih.../pmc/articles/PMC160888/

"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck

Pyroprone

#3
Posted : 7/11/2019 3:54:29 AM

[quote=benzyme]some people are already doing that.

and you’re just searching the wrong terms. You should be looking up Tryptophan biosynthesis and metabolism in plants.

https://www.ncbi.nlm.nih...pmc/articles/PMC160888/[/quote]

Awesome thanks for the point in the right direction!

benzyme

#4
Posted : 7/11/2019 4:05:27 AM

anytime.

"Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck

blue.magic

#5
Posted : 7/11/2019 6:44:00 PM

It's three enzymatic steps. More info here.

First the amino acid tryptophan is decarboxylated to tryptamine, which is then twice methylated.

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