The PICC is due to long antibiotic therapy of lymese disease.
In fact I am not considering this too seriously, as any IV or even IM was a no go for me in the past. This was one of my crucial rules when using any drugs to keep me safe. But that was another story, my relationship with drugs was not clear by that time. Now it is different and I think it would be ok to administer mescaline or dmt through PICC. I would have to be sure I know what I am doing though and I don't believe I can find someone with such knowledge.
Technically it wouldn't be problem, especially if it went through infusion. I doubt it would have any negative effect on veins with such dilution, the bag contains 250ml of the solution. Infection should not be a problem too, as I do the infusion everyday anyway, everything is sterile. I would just add mescaline to the physiological salt solution as I do with atb. The mescaline would be kept with 20ml of physiological salt solution for few minutes at 100C, sucked by sterile syringe and injected into the bag.
The PICC is in fact quite comfortable, I almost don't know about it. In fact every regular IV user would probably be thankful for such device

Acceptance of the fact that our reality is not real doesn't in fact mean it is not real. It just leads to better understanding what real means.