I recently took a small dose of synthetic 5-MeO-DMT. It was roughly 5 mg of the stuff, insufflated.
The experience was not overwhelmingly powerfull, so i don't think it gave me a good impression yet of what 5-MeO-DMT is capable of.
I took it when i was coming down from an LSD experience so there might have been some cross tolerance going on, but at the same time i was still feeling the effects of the LSD so the opposite could also be true.
But here's what i found realy interesting: the experience was remarkably simmilar to the yopo experiences that i've had thus far. So that seems to indicate to me that either there are active amounts of 5-MeO-DMT in yopo, or 5-MeO-DMT shares some of it's characteristics with yopo's main constituent, bufotenine.
It was a pretty euphoric experience. Yopo, taken in conjunction with other psychedelics, has often given me the sensation of slowly dissolving in vibrating, golden light. First everything starts becoming vibration, the objects in the room, the walls, and even space itself. Yopo is pretty visual, unlike 5-MeO-DMT, and it makes everything look like it is made of vibrating strings of golden light. Then i start to feel like i'm made of these strings myself as well, and i sort of melt into this web of light, and that is easily one of the most euphoric experiences i know.
The low dose of 5-MeO-DMT felt exactly like that, but without the visual component. It felt like slowly melting together with the room and everything in it, including the space of the room. It felt warm and vibrant. It felt like dissolving into pure energy. Very nice.
That sensation did not seem to last very long though. There was definately a peak, wich i guess lasted for maybe five to ten minutes, and then i was left with an undefined sort of warm, pleasant, trippy feeling that lasted for maybe another twenty to thirty minutes.
There was a bodyload, wich was relatively strong, but not uncomfortable. Just a feeling of increased gravity.
The only not so pleasant effect i experienced was a bit of a stingy feeling in the nose.
Considering the fact that i was not overwhelmed, i suppose i did only get a slight glimpse of what this substance is capable of. The way several nexians describe a full breakthrough experience, makes me believe a small dose is vastly different from a large dose, and also that this substance is to be treated with caution and respect. And given the fact that fellow nexians who've all taken DMT as well as many other powerfull psychedelics are saying this, i take this advice very seriously.
Yet, thus far i must say that i realy liked it.